Over time, the skin begins to lose its volume and elasticity, resulting in wrinkles and hollowness. Restylane® Refyne is designed to help correct and soften lines around the mouth such as nasolabial folds and marionette lines using patented XpresHAn Technology. The XpresHAn Techology is a specifically formulated flexible hyaluronic acid derma filler to help support natural expression and maintain natural movement in the face.

With over 30 million treatments worldwide and counting, the Restylane® family of hyaluronic acid fillers is used to help smooth away wrinkles and folds, such as nasolabial folds (Restylane®-L, Restylane® Refyne, Restylane® Defyne and Restylane® Lyft with Lidocaine), create fuller and more accentuated lips (Restylane® Silk and Restylane®-L), and add lift and volume to the cheeks (Restylane® Lyft with Lidocaine). All Restylane® products work to enhance facial features and give long-lasting, yet non-permanent results.

Restylane® Refyne and Restylane® Defyne were recently approved by the U.S. Food and Drug Administration (FDA) for the treatment of nasolabial folds (NLF) or “laugh lines,” in patients over the age of 21. Restylane® Refyne was approved for the treatment of moderate to severe facial wrinkles and folds, such as NLF.