Over time, the skin begins to lose its volume and elasticity, resulting in wrinkles and hollowness. Restylane® Defyne is designed to help correct and soften lines around the mouth such as nasolabial folds and marionette lines using patented XpresHAn Technology. The XpresHAn Techology is a specifically formulated flexible hyaluronic acid derma filler to help support natural expression and maintain natural movement in the face.

Restylane® Defyne may also be used to treat the chin region to improve the chin profile in patients with mild to moderate chin retrusion. Using a dermal filler in the chin region can help to improve the overall profile, shape, and size for more balance and proportion.

With over 30 million treatments worldwide and counting, the Restylane® family of hyaluronic acid fillers is used to help smooth away wrinkles and folds, such as nasolabial folds (Restylane®-L, Restylane® Refyne, Restylane® Defyne and Restylane® Lyft with Lidocaine), create fuller and more accentuated lips (Restylane® Silk and Restylane®-L), and add lift and volume to the cheeks (Restylane® Lyft with Lidocaine). All Restylane® products work to enhance facial features and give long-lasting, yet non-permanent results.

Restylane® Refyne and Restylane® Defyne were recently approved by the U.S. Food and Drug Administration (FDA) for the treatment of nasolabial folds (NLF) or “laugh lines,” in patients over the age of 21. Restylane® Refyne was approved for the treatment of moderate to severe facial wrinkles and folds, such as NLF.